{"id":1257,"date":"2025-11-12T12:32:44","date_gmt":"2025-11-12T12:32:44","guid":{"rendered":"https:\/\/stophemo.gr\/?p=1257"},"modified":"2026-03-26T18:45:50","modified_gmt":"2026-03-26T18:45:50","slug":"why-look-to-the-oceans-for-hemostasis","status":"publish","type":"post","link":"https:\/\/stophemo.gr\/en\/why-look-to-the-oceans-for-hemostasis\/","title":{"rendered":"WHY LOOK TO THE OCEANS\u2026. FOR HEMOSTASIS?"},"content":{"rendered":"<p>When it comes to stopping bleeding, your body is like a tiny, highly trained emergency<br \/>\nteam\u2014sending platelets, clotting factors, and a flood of chemical signals to patch up the<br \/>\ndamage before you even notice it. But sometimes even the best emergency team needs a<br \/>\nlittle backup to get the job done!<\/p>\n<h3>\n<strong>WHAT IS HEMOSTASIS?<\/strong><\/h3>\n<p>Hemostasis is the body\u2019s biological process for stopping bleeding after an injury to a blood<br \/>\nvessel. It is the first step in wound healing and consists of three main mechanisms:<br \/>\n\ud83d\udc49\ud83c\udffbVasoconstriction \u2014 blood vessels constrict to reduce blood flow.<br \/>\n\ud83d\udc49\ud83c\udffbPlatelet plug formation \u2014 platelets stick together to form an initial seal.<br \/>\n\ud83d\udc49\ud83c\udffbCoagulation \u2014 a cascade of chemical reactions turns blood into a gel (fibrin clot) to<br \/>\nfirmly stop bleeding.<br \/>\nHemostasis is a highly efficient natural process. However, in many real-world situations (such<br \/>\nas first aid emergencies or specific medical conditions), additional help is required to<br \/>\neffectively stop the bleeding. Such help sometimes comes \u2026. from the oceans!<\/p>\n<h3><strong>SEAWEED TO THE RESCUE: STOPPING BLEEDS NATURALLY<\/strong><\/h3>\n<p>Seaweed has a long history of use in traditional wound care, particularly among coastal<br \/>\ncommunities who relied on readily available marine resources. Fishermen and sailors used<br \/>\nto apply fresh or dried seaweed directly to cuts and wounds to help absorb blood,<br \/>\nprotect the injury, and promote healing.<\/p>\n<p>Brown seaweed was especially valued because of their soft texture when wet and their ability<br \/>\nto hold moisture, which helped cover wounds and limit continued bleeding.<\/p>\n<p>Over time, scientists discovered that compounds within these seaweeds\u2014especially alginates\u2014were responsible<br \/>\nfor many of the beneficial effects observed in traditional use, allowing ancient knowledge to<br \/>\nbe transformed into modern, evidence-based wound care materials.<\/p>\n<h4><strong>FROM TRADITIONAL USE TO SCIENTIFIC EVIDENCE AND INDUSTRIAL<\/strong><br \/>\n<strong>APPLICATIONS<\/strong><\/h4>\n<p>Alginate (also called alginic acid) was first discovered in the nineteenth century by the British<br \/>\nchemist E. C. C. Stanford, who extracted this natural substance from a brown seaweed<br \/>\nvariety called Laminaria. Early publications and studies focused on its physical and chemical<br \/>\nproperties, such as its ability to absorb fluids, form viscous solutions, and create gels.<\/p>\n<p>While alginate was initially exploited in industries such as food, textiles, and paper, its<br \/>\nbiocompatibility and gel-forming properties led the pharmaceutical industry to adopt it in the<br \/>\nmid-20\u1d57\u02b0 century as a versatile excipient used to support and control drug delivery.<br \/>\nSeaweeds \u2014 especially brown seaweeds \u2014 are large marine algae<br \/>\nrich in natural polysaccharides such as alginate. These polymers have<br \/>\nunique physical and chemical properties that make them useful in<br \/>\nwound care.<\/p>\n<p>Alginate is extracted from the cell walls of brown seaweed such as<br \/>\nLaminaria species. It contains molecular blocks of mannuronic and<br \/>\nguluronic acid that can form gels when in contact with fluids.<\/p>\n<p>Around the same time, specific interest in the hemostatic potential of alginate emerged<br \/>\nthrough the work of British surgeon George Blaine, who, during the 1940s, investigated<br \/>\ncalcium alginate use on wounds. Blaine observed that when applied to bleeding wounds,<br \/>\ncalcium alginate not only absorbed blood but also promoted clot formation by releasing<br \/>\ncalcium ions\u2014an essential factor in the coagulation process.<\/p>\n<p>In France, surgeon Jean Gosset was among the first clinicians to draw attention to the<br \/>\nhemostatic potential of alginate materials. At a 1949 session of the Acad\u00e9mie de Chirurgie<br \/>\n(Academy of Surgery) in Paris, Gosset shared clinical observations using calcium alginate on<br \/>\nvarious wounds and concluded that it offers genuine potential. He encouraged its preparation<br \/>\non a commercial scale and supported the launch of Coalgan\u00ae in 1949<\/p>\n<p><a href=\"https:\/\/www.coalgan-gamme.com\/\">www.coalgan-<\/a>gamme.com<\/p>\n<p>The works of Blaine and Gosset marked the first serious clinical explorations of alginate as a<br \/>\nmedical material, transforming a natural seaweed extract into a scientifically recognized<br \/>\nhemostatic agent. This paved the way for the development of calcium alginate medical<br \/>\ndevices used in advanced wound care for hemostasis and tissue repair (www.brothier.com).<\/p>\n<h4><strong>HOW STOP HEMO\u00ae STOPS BLEEDING: MECHANISM OF ACTION<\/strong><\/h4>\n<p>Inspired by the natural properties of algae, Stop H\u00e9mo\u00ae changes upon contact with blood.<br \/>\nThis physical and chemical transformation allows it to act both mechanically and biologically,<br \/>\npromoting effective coagulation. Its calcium alginate:<br \/>\n1- Absorbs blood<br \/>\n2- Hydrates and forms a protective gel, which acts like a temporary barrier, trapping<br \/>\nblood cells and clotting factors at the wound site<br \/>\n3- Releases calcium ions at bleeding site (calcium ions are factor IV of the coagulation<br \/>\ncascade, essential for the clotting process)<br \/>\n4- Does not stick to the newly formed clot: the gelified structure ensures an atraumatic<br \/>\nremoval.<br \/>\nThis nature-inspired action makes it a suitable first-aid solution for everyday situations.<br \/>\nReady to use and designed for life\u2019s unexpected moments, it offers calm and confidence<br \/>\nCoalgan\u00ae, a hemostatic swab indicated for the treatment of minor<br \/>\nnosebleeds, is made of calcium alginate fibers and thus delivers the<br \/>\nhemostatic properties of algae. It is nowadays internationally available<br \/>\nunder the brand names <a href=\"https:\/\/stophemo.gr\/en\/\">Stop H\u00e9mo\u00ae<\/a>, BleedCease\u00ae, NasalCease\u00ae and<br \/>\nChicare\u00ae (www.brothier.com)<\/p>\n<h4><strong>KEY POINTS TO BEAR IN MIND<\/strong><\/h4>\n<p>The story of seaweed in medicine is one of transformation: from traditional use along coastlines<br \/>\nto sophisticated biomedical treatments in modern households and hospitals.<br \/>\nSeaweed\u2019s physical and chemical properties are particularly useful in hemostasis: it absorbs<br \/>\nblood, hydrates, forms a protective gel and releases its calcium ions at the bleeding site to<br \/>\nsupport the natural process of coagulation. Those properties, once observed by sailors, have<br \/>\nsince been harnessed and refined through industrial processing\u2014transforming alginate into<br \/>\nhemostatic and healing medical devices.<\/p>\n<p>Thus, the ocean gave us a powerful resource, and we used it wisely &#8211; advancing patient care<br \/>\nwhile reinforcing our responsibility to protect marine ecosystems.<\/p>\n<p>Join the movement by exploring the work of our partner, <a href=\"https:\/\/www.1ocean.org\/\">1Ocean<\/a>, and be part of a more sustainable future for<br \/>\nhealthcare, the ocean and the climate: <a href=\"https:\/\/www.mission-1ocean.com\/projet\/forets-sous-marines-un-enjeu-pour-lhumanite\/\">https:\/\/www.mission-1ocean.com\/projet\/forets-sous-<\/a><br \/>\nmarines-un-enjeu-pour-lhumanite\/ Restoring our underwater forests is more than protecting biodiversity,<br \/>\nit\u2019s a bold step toward safeguarding our climate for the future.<br \/>\n\u2014 Alexis Rosenfeld, Project Leader at 1 OCEAN<\/p>\n<p>when bleeding occurs &#8211; whether from a sudden nosebleed, delicate gum bleeding, or a minor<br \/>\nskin injury &#8211; helping you care for yourself and your loved ones when it matters most.<\/p>\n<h4><strong>SUSTAINABILITY AND THE FUTURE OF SEAWEED IN MEDICINE<\/strong><\/h4>\n<p>As sustainability becomes a central concern in healthcare, seaweed stands out as a natural<br \/>\nresource uniquely suited to meet both medical and environmental challenges. Unlike<br \/>\nterrestrial crops, seaweed doesn\u2019t require fertilizer, pesticides, freshwater, or land, and it<br \/>\ngrows rapidly.<br \/>\nThis ease of cultivation and exceptional sustainability are matched by a rich biochemical<br \/>\ndiversity, positioning seaweed as both an environmentally responsible resource and a<br \/>\npromising source of therapeutic compounds.<br \/>\nSeaweeds are rich in polysaccharides, polyphenols, proteins, and pigments, which possess<br \/>\nvarious therapeutic properties. These compounds have shown potential as anti-inflammatory,<br \/>\nantimicrobial, antiviral, antitumor, and antioxidant agents, among others.<br \/>\nStay tuned for our publication regarding seaweed benefits in healing by reducing<br \/>\ninflammation, fighting bacteria, and promoting tissue growth!<\/p>\n<p>Sources:<br \/>\n1. <a href=\"https:\/\/my.clevelandclinic.org\/health\/symptoms\/21999-hemostasis\">Hemostasis, https:\/\/my.clevelandclinic.org\/health\/symptoms\/21999-hemostasis, accessed<\/a><br \/>\non 06\/01\/2026.<br \/>\n2. P\u00e9rez-Llor\u00e9ns, J.L., Critchley, A.T., Cornish, M.L.\u00a0et al.\u00a0Saved by seaweeds (II):<br \/>\nTraditional knowledge, home remedies, medicine, surgery, and pharmacopoeia.\u00a0J Appl<br \/>\nPhycol\u00a035, 2049\u20132068 (2023). https:\/\/doi.org\/10.1007\/s10811-023-02965-6.<br \/>\n3. Hylenne\u00a0Bojorges,\u00a0 Amparo\u00a0L\u00f3pez-Rubio ,\u00a0 Antonio\u00a0Mart\u00ednez-Abad ,\u00a0 Mar\u00eda Jos\u00e9\u00a0Fabra ,<br \/>\nOverview of alginate extraction processes: Impact on alginate molecular structure and<\/p>\n<p>techno-functional properties, Trends in Food Science &amp;amp; Technology, Volume<br \/>\n140,\u00a0October 2023. https:\/\/doi.org\/10.1016\/j.tifs.2023.104142<br \/>\n4. Blaine G. Experimental Observations on Absorbable Alginate Products in Surgery : Gel,<br \/>\nFilm, Gauze and Foam. Ann Surg. 1947 Jan;125(1):102-14. doi: 10.1097\/00000658-<br \/>\n194701000-00011. PMID: 17858907; PMCID: PMC1803201.<br \/>\n5. Histoire de l\u2019h\u00e9mostase locale, Acad\u00e9mie de Chirurgie Magazine, 3 \u00e8me trimestre 2012.<br \/>\n6. Pereira L, Cotas J. Seaweed: a sustainable solution for greening drug manufacturing in<br \/>\nthe pursuit of sustainable healthcare. Explor Drug Sci.<br \/>\n2024;2:50\u201384.\u00a0https:\/\/doi.org\/10.37349\/eds.2024.00036<br \/>\nNET26SHE03A \u2013 janv 2026<\/p>\n","protected":false},"excerpt":{"rendered":"<p>When it comes to stopping bleeding, your body is like a tiny, highly trained emergency team\u2014sending platelets, clotting factors, and a flood of chemical signals to patch up the damage before you even notice it. But sometimes even the best emergency team needs a little backup to get the job done! WHAT IS HEMOSTASIS? Hemostasis [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":1137,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[15,13,14],"tags":[],"class_list":["post-1257","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-and-wellness","category-nosebleeds","category-superficial-wounds"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>WHY LOOK TO THE OCEANS\u2026. 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